ISSN Print 2713-2757
ISSN Online 2713-2765
Extreme Medicine
SCIENTIFIC AND PRACTICAL REVIEWED JOURNAL OF FMBA OF RUSSIA
REVIEW
Calculation of reference intervals of blood parameters in children and adolescents: projects review
About authors
Federal Research and Clinical Center for Sports Medicine and Rehabilitation of the Federal Medical Biological Agency, Moscow, Russia
Correspondence should be addressed: Zhanna V. Grishina
B. Dorogomilovskaya, 5, Moscow, 121059, Russia; moc.liamg@ktenaznirg
About paper
Funding: the study was performed as part of the applied research project “Developing the Guidelines on Increasing the Efficiency of the Measures for Medical and Biological Support of Juvenile Athletes of Russian National Teams” (code “Deti-22”), the Federal Research and Clinical Center of Sports Medicine and Rehabilitation of the Federal Medical Biological Agency State Assignment №107.002.22.14 of 11.07.2022.
Author contribution: Grishina ZhV, Klyuchnikov SO — data acquisition and processing, manuscript writing, editing; Feshchenko VS, Zholinskiy AV — editing, approval of the manuscript final version.
Received: 2023-03-02
Accepted: 2023-03-17
Published online: 2023-03-26
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The review of the currently existing projects focused on calculating the reference intervals of blood parameters in large samples of children of different gender and age discusses the urgent issues of calculating pediatric reference intervals of biochemical markers, the paper provides comparison of the reference intervals established within the framework of different projects. The limitations, future prospects and harmonization of pediatric reference intervals, including for juvenile athletes, are provided.
Keywords: pediatrics, children, reference intervals, blood parameters, juvenile athletes, sports medicine