OPINION
Mechanisms of SARS-CoV-2 effect on human body: unobvious pathogenetic links
1 Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency, Moscow, Russia
2 Research and Testing Center for Aviation Space and Military Ergonomics, Moscow, Russia
3 Russian Center for Disaster Medicine “Zashchita” of FMBA of Russia, Moscow, Russia
4 National Medical Research Center Rehabilitation and Balneology, Moscow, Russia
Correspondence should be addressed: Igor B. Ushakov
123098, Russia, Moscow, Zhivopisnaya str., 46; ur.abmfcbmf@vokahsui
The authors formulated a hypothesis about an important link in the pathogenesis of COVID-19, in which the increasing hypoxia and an acute response of the body like a general adaptation syndrome, accompanied by systemic pathological changes, including dangerous disorders of rheology and blood coagulation, play a key role.
Keywords: neutrophils, cytokines, coronavirus, lymphocytes, COVID-19, SARS-CoV-2, hypoxia general adaptation syndrome, cortisol immunity, monocytes