Fig. 1. Heat map of keyword (MeSH terms and authors' terms) mention frequency in the paper's abstracts

Fig. 2. Distribution of keyword (MeSH terms and authors' terms) co-occurrence based on the bibliographic data analysis

Fig. 3. The distribution of major groups of non-peptide organic compounds as new anticancer drug prototypes

Fig. 4. Heat map of changes in publication activities (2016–2020) on identifying the new anticancer drug prototypes. Note: legend scale — cluster distance; decrease and increase in the number of papers are highlighted in red and blue colors, respectively

Fig. 5. Сitations of papers issued in 2019 and focused on the anticancer drug prototype identification. Original names of compounds are provided Total number of citations for papers issued in 2019

Fig. 6. Associations between the protein targets of anticancer drug prototypes returned by the queries “malignant transformation” and “cancer progression” in the Pathway Studio