2021 / 03

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DOI: 10.47183/mes.2021.035

ORIGINAL RESEARCH

Molecular genetic characterization of three new Klebsiella pneumoniae bacteriophages suitable for phage therapy

Gorodnichev RB, Kornienko MA, Kuptsov NS, Malakhova MV, Bespiatykh DA, Veselovsky VA, Shitikov EA, Ilina EN
About authors

Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, Moscow, Russia

Correspondence should be addressed: Roman B. Gorodnichev
Malaya Pirogovskaya, 1а, Moscow, 119435; moc.liamg@b.r.vehcindorog

About paper

Funding: the study was carried out within the framework of the State Assignment "Development of a Personalized Approach to the Therapy of Infections Using Virulent Bacteriophages" (CODE: Bacteriophage).

Acknowledgements: the authors thank the Center for Precision Genome Editing and Genetic Technologies for Biomedicine, the Federal Research and Clinical Center of Physical-Chemical Medicine of the Russian Federal Medical Biological Agency, for their help with bacteriophage genome sequencing.

Author contribution: Gorodnichev RB, Kornienko MA, Shitikov EA — study plan, data processing, manuscript writing; Kuptsov NS — data acquisition and processing, manuscript writing; Malakhova MV, Veselovsky VA — data acquisition; Bespiatykh DA — data processing, Ilina EN — study plan, manuscript writing.

Compliance with ethical standards: experimental work was carried out in strict compliance with the guidelines SP 1.3.2322-08 "Safety of Working With Microorganisms of III–IV Groups of Pathogenicity (Danger) and Causative Agents of Parasitic Diseases"; guidelines SP 1.3.2518-09 “Additions and Amendments № 1 to the guidelines SP 1.3.2322-08 "Safety of Working With Microorganisms of III–IV Groups of Pathogenicity (Danger) and Causative Agents of Parasitic Diseases"; guidelines "Sanitary and Epidemiologic Requirements for the Handling of Medical Waste" (SanPiN 2.1.7.2790-10), and Federal Clinical Guidelines "Rational Use of Bacteriophages in Clinical and Epidemiological Practice".

Received: 2021-07-21 Accepted: 2021-08-26 Published online: 2021-09-29
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