ORIGINAL RESEARCH

Molecular genetic characterization of three new Klebsiella pneumoniae bacteriophages suitable for phage therapy

About authors

Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, Moscow, Russia

Correspondence should be addressed: Roman B. Gorodnichev
Malaya Pirogovskaya, 1а, Moscow, 119435; moc.liamg@b.r.vehcindorog

About paper

Funding: the study was carried out within the framework of the State Assignment "Development of a Personalized Approach to the Therapy of Infections Using Virulent Bacteriophages" (CODE: Bacteriophage).

Acknowledgements: the authors thank the Center for Precision Genome Editing and Genetic Technologies for Biomedicine, the Federal Research and Clinical Center of Physical-Chemical Medicine of the Russian Federal Medical Biological Agency, for their help with bacteriophage genome sequencing.

Author contribution: Gorodnichev RB, Kornienko MA, Shitikov EA — study plan, data processing, manuscript writing; Kuptsov NS — data acquisition and processing, manuscript writing; Malakhova MV, Veselovsky VA — data acquisition; Bespiatykh DA — data processing, Ilina EN — study plan, manuscript writing.

Compliance with ethical standards: experimental work was carried out in strict compliance with the guidelines SP 1.3.2322-08 "Safety of Working With Microorganisms of III–IV Groups of Pathogenicity (Danger) and Causative Agents of Parasitic Diseases"; guidelines SP 1.3.2518-09 “Additions and Amendments № 1 to the guidelines SP 1.3.2322-08 "Safety of Working With Microorganisms of III–IV Groups of Pathogenicity (Danger) and Causative Agents of Parasitic Diseases"; guidelines "Sanitary and Epidemiologic Requirements for the Handling of Medical Waste" (SanPiN 2.1.7.2790-10), and Federal Clinical Guidelines "Rational Use of Bacteriophages in Clinical and Epidemiological Practice".

Received: 2021-07-21 Accepted: 2021-08-26 Published online: 2021-09-29
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