Acknowledgements: we would like to express our gratitude to Evgeny B. Faizuloev (Mechnikov Research Institute of Vaccines and Sera) for the provided virus. The study was performed using the equipment provided by the Center for Collective Use of the Mechnikov Research Institute of Vaccines and Sera.

Author contribution: Ryabchenkova AA — study concept and design, data analysis and interpretation, manuscript writing; Kopat VV — concept, design, and organization of research, manuscript writing; Chirak ER, Chirak EL — study design, preparation of samples and materials; Leneva IA — experimental procedures, data acquisition, analysis, and interpretation; Kartashova NP, Glubokova EA — experimental procedures; Kolmakov NN — study concept, manuscript editing; Dukhovlinov IV — initiation, project management, developing the concept of drug composition, organization of research funding.

Compliance with ethical standards: the study was performed in accordance with the principles of the World Medical Association Declaration of Helsinki.