Features of bioelectric activity of the retrosplenial cortex

About authors

1 Institute for Physics and Engineering in Biomedicine, National Research Nuclear University MEPhI, Moscow, Russia

2 La Salute Clinic, Moscow, Russia

Correspondence should be addressed: Sergey A. Gulyaev
Ramenki, 31, k. 136, Moscow, 119607, Russia; moc.liamg@37veaylug.s

About paper

Author contributions: Gulyaev SA — study concept, clinical neurophysiological assessment, statistical analysis of the results; Khanukhova LM — research organization; Garmash AA — general management.

Compliance with ethical standards: the study was approved by the Ethics Committee of the National Research Nuclear University MEPhI (protocol № 05/23 of 25 May 2023) and conducted in accordance with the principles of biomedical ethics set out in the Declaration of Helsinki (1964) and its subsequent updates.

Received: 2023-06-27 Accepted: 2023-09-04 Published online: 2023-09-25

Human brain is one of the most difficult organs to study. The possibility of developing the technologies that have sufficient scientific accuracy and economic accessibility and never violate the moral and ethical standards of human society is of great interest. The study was aimed to study the possibility of assessing the retrosplenial cortex (RSC) structures’ activity based on the EEG analysis of brain activity in the alpha frequency range in 36 healthy volunteers with an average age of 29.1 years, no acute central nervous system disorders or exacerbation of chronic central nervous system disorders, severe traumatic brain injuries, mental disorders or epilepsy. Significant source localizations were obtained by solving the EEG inverse problem that could be used for identification of the cerebral retrosplenial cortex structures’ bioelectric activity. The use of such technology will allow us to expand the scope of the research focused on assessing the brain functional activity in both research and clinical centers, thereby paving the way for understanding the features of the brain structures’ activity in physiologically normal conditions and in individuals with mental disorders caused by various functional alterations in the brain.

Keywords: electroencephalography, mathematical methods, retrosplenial cortex, bioelectrical activity of the brain