Funding: the work was carried out as part of the research effort under the State Assignment.

Acknowledgements: the authors express gratitude to the staff of the Center for Laboratory Research of the Clinic of the Russian Research Institute of Hematology and Transfusiology of the Federal Medical and Biological Agency of Russia for laboratory support.

Author contribution: Concept and Design: all authors.

Compliance with ethical standards: the study was approved by the ethics committee of the Russian Research Institute of Hematology and Transfusiology of the Federal Medico-Biological Agency of Russia (Minutes № 61 of December 22, 2022); all study participants-donors signed a voluntary informed consent for blood sampling and further analysis.