ORIGINAL RESEARCH

The role of fast running in prevention of negative effects of prolonged exposure to weightlessness

Fomina EV, Senatorova NA, Bakhtereva VD, Yarmanova EN, Kozlovskaya IB
About authors

State Scientific Center of Russian Federation — Institute of Biomedical Problems RAS, Moscow, Russia

Correspondence should be addressed: Elena V. Fomina
Khoroshevskoe shosse, 76A, Moscow, 123007, Russia; ur.xednay@nimof-nimof

About paper

Funding: the work was financially supported by the Russian Academy of Sciences (63.1) and Roscosmos State Corporation.

Acknowledgements: we express our gratitude to the cosmonauts for participating in the experiment (Yuri Gagarin Cosmonaut Training Center); Lysova N.Yu, senior researcher, Candidate of Biological Sciences, (Institute of Biomedical Problems); Rezvanova S.V. (Center for Innovative Sports Technology and National Teams Training) for participation in the experiment and data collection; Beda O.O. for supporting the experiment's sessions in the MCC; Smirnov Yu.I. for participation in the preparation of documentation; Kukoba T.B, Babich D.R., Romanov P.V. for development of the individual strength training protocols and strength training supervision during the space flight.

Author contribution: Fomina EV — organization and support of the Profilactika-2 experiment, conducting sessions of the experiment, article authoring; Senatorova NA — conducting sessions of the experiment, support of the experiment, statistical processing of the results, literary review and arrangement of the article; Bakhtereva VD — data processing, article authoring; Yarmanova EN — engineering support of countermeasures, development of the BD-2 treadmill in collaboration with I.B. Kozlovskaya; Kozlovskaya IB — selection/formulation of goals, objectives and methods of the experiment.

Compliance with ethical standards: the Profilactika-2 experiment was approved by the Ethics Committee of the Institute of Biomedical Problems (Minutes #368 of August 22, 2014). All participants signed a voluntary informed consent form.

Received: 2023-06-15 Accepted: 2023-10-15 Published online: 2023-11-19
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Fig. 1. Heart rate as registered with the IST before and after the space flight. * — compared to the preflight level in the group, p < 0.05
Fig. 2. Pulmonary ventilation before and after the space flight, as registered with the IST. * — compared to the preflight level in the group, p < 0.05
Fig. 3. Capillary blood lactate concentration, first minute of recovery after the IST. * — compared to the pre-flight level in the group, p < 0.05; 1 — days 42–68, 2 — days 83–113, 3 — days 115–131, and 4 — days 140–156
Fig. 4. Total heart rate value registered during the IST. * — p < 0.05 compared to the background value in the group; @ — p < 0.05 in comparison with the value of the same flight period in group A; 1 — days 42–68, 2 — days 83–113, 3 — days 115–131, and 4 — days 140–156 of the flight
Fig. 5. Total recovery heart rate value registered during the IST. * — p < 0.05 compared to the background value in the group; @ — p < 0.05 in comparison with the value of the respective flight period in group A; 1 — days 42–68, 2 — days 83–113, 3 — days 115–131, and 4 — days 140–156 of the flight