ORIGINAL RESEARCH

Laser therapy and unloading therapeutic gymnastics in the treatment of dyslipoproteinemia

Achilov AA1,2, Baranov AV1, Gornov SV2, Usmonzoda DU4, Achilova SA5, Pulatova MD6, Achilov AlA3, Mamedyarova IA7, Lazechko MI1
About authors

1 The Skobelkin Research and Practical Centre for Laser Medicine of the Federal Medical-Biological Agency, Moscow, Russia

2 Russian Biotechnological University, Institute of Medical Continuous Education, Moscow, Russia

3 Vishnevsky Central Military Clinical Hospital of the Russian Federation Defence, Moscow, Russia

4 Diagnostic Clinical Center № 1 of the Moscow City Health Department, Branch 3. Moscow, Russia

5 SCOLMED LLC, Zarechye, Moscow, Russia

6 Municipal Polyclinic № 134 of the Moscow City Health Department, Moscow, Russia

7 Azerbaijan Medical University, Baku, Azerbaijan

Correspondence should be addressed: Maryana I. Lazechko
Studentcheskaya, 40, Moscow, 121165, Russia; ur.demsalsog@m.okhcezal

About paper

Author contribution: Achilov AA — methodology development, collection and statistical processing of data, manuscript writing; Baranov AV — study concept, scientific supervision, manuscript editing; Gornov SV — study concept, scientific supervision, literature review, manuscript writing; Usmonzoda DU — data collection, literature review, manuscript writing; Achilova SA, Pulatova MD, Achilov Al.A, Mamedyarova IA — data collection, literature review; Lazechko MI — literature review, study design, manuscript editing.

Compliance with ethical standards: the study was approved by the Ethics Commitee of the Skobelkin Research and Practical Centre for Laser Medicine of the Federal Medical-Biological Agency (protocol № 2/23 dated 18 December 2023). All patients submitted the informed consent to study participation.

Received: 2023-12-19 Accepted: 2024-02-24 Published online: 2024-03-25
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  1. Achilov AA, inventor. Method for preventing, treating and regressing hypertonic disease, atherosclerosis, ischemic cardiac disease, circulatory insufficiency. Russian Federation patent № 2245700. 10.02.2005. Russian.
  2. Achilov AA, Baranov AV, Achilova ShA, Lebedeva OD, Kornev OD, Airapetova TL. Optimization of complex treatment of patients with severe arterial hypertension. Clin Gerontol. 2021; 27 (1–2): 76–83. Russian.
  3. Achilov AA, inventor. Method for preventing, treating and regressing hypertonic disease, atherosclerosis, ischemic cardiac disease, circulatory insufficiency. Evraziyskiy patent № 004621 от 24.06.2004. Russian.
  4. Karpov YuA. How to enhance control of low-density lipoprotein cholesterol in reducing cardiovascular risk? Atmosfera. Novosti kardiologii. 2021; 1: 3–12. Russian.
  5. Karpov YuA. Efficacy and safety of achieving novel low-density lipoprotein cholesterol target levels: the role of combination therapy. Atmosfera. Novosti kardiologii. 2021; 2: 3–11. Russian.
  6. Karpov YuA, Barbarash OL, Boschenko AA, Kashtalap VV, Kukharchuk VV, et al. Eurasian Guidelines for the diagnostics and management of stable coronary artery disease (2020–2021). Eurasian heart journal. 2021; № 3 (36): 54–93. Russian.
  7. Giugliano RP, Pedersen TR, Park JG, et al. Clinical efficacy and safety of achieving very low LDL-cholesterol concentrations with the PCSK9 inhibitor evolocumab: a prespecified secondary analysis of the FOURIER trial. The Lancet. 2017; 390 (10106): 1962–71. DOI: 10.1016/S0140-6736(17)32290-0.
  8. Bhatt DL, Steg PG, Miller M, et al. Cardiovascular risk reduction with icosapent ethyl for hypertriglyceridemia. New England Journal of Medicine. 2019; 380 (1): 11–22. DOI: 10.1056/NEJMoa1812792.
  9. Cholesterol Treatment Trialists’ Collaboration. Efficacy and safety of statin therapy in older people: a meta-analysis of individual participant data from 28 randomised controlled trials. The Lancet. 2019; 393 (10170): 407–15. DOI: 10.1016/S0140-6736(18)31942-1.
  10. Rohit D, Shankar J. Comparative Study of Atorvastatin and Rosuvastatin in Combination with Fenofibrate in mixed Hyperlipidemia. Int J Pharmacol and Clin Sci. 2016; 5 (1): 25–31.
  11. Lee J, Egolum U, Parihar H, et al. Effect of Ezetimibe Added to High-Intensity Statin Therapy on Low-Density Lipoprotein Cholesterol Levels: A Meta-Analysis. Cardiol Res. 2021; 12 (2): 98–108. DOI: 10.14740/cr1224.
  12. Ray KK, Reeskamp LF, Laufs U, et al. Combination lipid-lowering therapy as first-line strategy in very high-risk patients. Eur Heart J. 2022; 43 (8): 830–3. DOI: 10.1093/eurheartj/ ehab718.
  13. Burnett H, Fahrbach K, Cichewicz A, et al. Comparative efficacy of nonstatin lipidlowering therapies in patients with hypercholesterolemia at increased cardiovascular risk: a network meta-analysis. Curr Med Res Opin. 2022; 38 (5): 777–84. DOI: 10.1080/0300799 5.2022.2049164.
  14. Khan SA, Naz A, Qamar Masood M, Shah R. Meta-Analysis of Inclisiran for the Treatment of Hypercholesterolemia. Am J Cardiol. 2020; 134: 69–73. DOI: 10.1016/j.amjcard.2020.08.018.
  15. Lloyd-Jones DM, Morris PB, Ballantyne CM, et al. 2022 ACC Expert Consensus Decision Pathway on the Role of Nonstatin Therapies for LDL-Cholesterol Lowering in the Management of Atherosclerotic Cardiovascular Disease Risk: A Report of the American College of Cardiology Solution Set Oversight Committee. J Am Coll Cardiol. 2022; 80 (14): 1366–418. DOI: 10.1016/j.jacc.2022.07.006.
  16. Kukharchuk VV, Ezhov MV, Sergienko IV, Arabidze GG, Bubnova MG, et al. Diagnostics and correction of lipid metabolism disorders in order to prevent and treat of atherosclerosis Russian recommendations VII revision. The Journal of Atherosclerosis and Dyslipidemias. 2020; 1 (38): 7–40. Russian.
  17. Moriarty PM, Thompson PD, Cannon CP, et al. Efficacy and safety of alirocumab vs ezetimibe in statin-intolerant patients, with a statin rechallenge arm: the ODYSSEY ALTERNATIVE randomized trial. Journal of clinical lipidology. 2015; 9 (6): 758–69. DOI: 10.1016/j.jacl.2015.08.006.
  18. Nissen SE, Stroes E, Dent-Acosta RE, et al. Efficacy and tolerability of evolocumab vs ezetimibe in patients with muscle-related statin intolerance: the GAUSS-3 randomized clinical trial. Jama. 2016; 315 (15): 1580–90. DOI: 10.1001/jama.2016.3608.
  19. Schreml J, Gouni-Berthold I. Role of anti-PCSK9 antibodies in the treatment of patients with statin intolerance. Current medicinal chemistry. 2018; 25 (13): 1538–48. DOI: 10.2174/0929867324666170616111647.
  20. Amirov NB. Mekhanizmy terapevticheskogo lazernogo vozdeystviya v klinike vnutrennikh bolezney (obzor literatury). Ieroglif. 2002; 5 (20): 27–34. Russian.
  21. Amirov NB, Abdrakhmanova AI, Akhunova SYu, Galeev AA, Serdyuk IL. Ishemicheskaya bolezn' serdtsa v obshchey vrachebnoy praktike: Diagnostika, i kompleksnaya medikamentozno-lazernaya terapiya. Kazan': Kazanskiy gosudarstvennyy meditsinskiy universitet, 2006; 144 p. Russian.
  22. Amirov NB. Nizkointensivnoe lazernoe izluchenie pri lechenii ishemicheskoy bolezni serdtsa. Fundamental'nye issledovaniya. 2008; 5: 14–6. Russian.
  23. Amirov NB, Abdrahmanova AI. Modern concepts on the mechanisms of low level laser therapy. Bulletin of Contemporary Clinical Medicine. 2015; 8 (5): 7–12. Russian.
  24. Abdrakhmanova AI, Amirov NB. Laser therapy in ischemic heart disease treatment. The Bulletin of Contemporary Clinical Medicine. 2019; 12 (6): 77–82. DOI: 10.20969/VSKM.2019.12(6).77-82. Russian.
  25. Achilov AA, Baranov AV, Achilova ShA, Karandashov VI, Gladko OV. Low-level laser therapy and unloading curative gymnastics in the complex treatment of severe arterial hypertension. Laser Medicine. 2018; 22 (4): 6–10. Russian.
  26. Bobrovnitskii IP, Nagornev SN, Yakovlev MYu, Uyanaeva AI, Khudov VV, et al. Methodology of personalized non–pharmacological prevention weather sensitivity common diseases of the circulatory system as the basis for an active healthy longevity. Bulletin of Rehabilitation Medicine. 2017; 1 (77): 72–8. Russian.
  27. Razumov AN. O dostizhenii natsional'nykh tseley razvitiya rossiyskoy federatsii na period do 2024 g. v chasti vliyaniya sanatorno-kurortnogo ozdorovleniya, vosstanovitel'nogo lecheniya i meditsinskoy nauki na zdorov'e sberezhenie naseleniya. Problems of Balneology, Physiotherapy and Exercise Therapy. 2019; 96 (2–2): 5–9. Russian.
  28. Razumov AN. Recovery medicine as a qualitative new level of modern healthcare. Lechebnoe delo: nauchno-prakticheskiy terapevticheskiy zhurnal. 2018; 1 (59): 55–63. Russian.
  29. Oganov RG, Maslennikova GIa, Imaeva AE. Prevention of noncommunicable diseases in the activities of the Northern Dimension Partnership in Health and Social Well-being: present and future. Profilakticheskaya Meditsina. 2019; 22 (1): 5–11. Russian.
  30. Razumov AN, Kotenko KV, Korchazhkina NB. Strategy and modern technology improvement of the population of the Russian Federation. Chief Medical Officer. 2016; 10: 6–25. Russian.
  31. Oganov RG. Importance of the epidemiologic studies and evidence-based medicine for clinical practice. Cardiovascular Therapy and Prevention. 2015; 14 (4): 4–7. Russian.
  32. Kobalava ZhD, Konradi AO, Nedogoda SV. Arterial hypertension in adults. Clinical guidelines 2020. Russian Journal of Cardiology. 2020; 25 (3): 149–218. Russian.
  33. Achilov AA, Almazov II, Kulikova TV, Borisova GA, Sidorenko BA. Sostoyanie mikrotsirkulyatornogo rusla, gemoperfuzii i kislorodnogo rezhima tkani u bol'nykh ishemicheskoy bolezn'yu serdtsa so stenokardiey. Ter. Arkhiv. 1984; 6: 39–43. Russian.