2024 / 02

Next Paper
DOI: 10.47183/mes.2024.033

ORIGINAL RESEARCH

Secondary hyperparathyroidism associated with vitamin D deficiency in young highly trained athletes

Isaeva EP1,3,4, Okorokov PL1,2, Zyabkin IV1,3
About authors

1 Federal Research and Clinical Center for Children and Adolescents of the Federal Medical Biological Agency, Moscow, Russia

2 Endocrinology Research Centre, Moscow, Russia

3 Medical and Biological University of Innovation and Continuing Education of the Federal Medical Biophysical Center named after A. I. Burnazyan of the Federal Medical and Biological Agency of Russia

4 Russian University of Medicine of the Ministry of Health of the Russian Federation, Moscow, Russia

Correspondence should be addressed: Elena P. Isaeva
Moskvorechye, 20, 115409, Moscow, Russia; ur.liam@4747arod

About paper

Author contribution: Isaeva EP — developing the research protocol, data acquisition, processing and interpretation of the results, manuscript writing; Okorokov PL — data acquisition, critical interpretation of the results, manuscript writing; Zyabkin IV — approving the research protocol and the final version of the manuscript.

Compliance with the ethical standards: the study was approved by the Ethics Committee of the Gaaz Moscow Medical and Social Institute (protocol No. 4 dated 04 October 2021). The athletes’ parents/caregivers or legal representatives submitted the informed consent to participation in the study.

Received: 2024-05-23 Accepted: 2024-06-15 Published online: 2024-06-30
|
  1. Zaharova IN, Malcev SV, Borovik TYe, i dr. Rezul'taty mnogocentrovogo kogortnogo issledovanija «RODNIChOK» po izucheniju nedostatochnosti vitamina D u detej rannego vozrasta v Rossii. Pediatrija. Zhurnal im. G.N. Speranskogo 2015; 94 (1): 62–67. Russian.
  2. Stoljarova SA, Okorokov PL, Zjabkin IV, Isaeva EP. Ocenka obespechennosti vitaminom D junyh sportsmenov. Pediatrija. Zhurnal im. G.N. Speranskogo 2023; 102 (5): 116–21. DOI: 10.24110/0031-403X-2023-102-5-116-121. Russian.
  3. Melnichenko GA, Namazova-Baranova LS, Gromova OA, i dr. Profilaktika i lechenie deficita vitamina D: vybor optimal'nogo podhoda. Voprosy sovremennoj pediatrii. 2021; 20 (4): 338–45. Dostupno po ssylke: https://doi.org/10.15690/vsp.v20i4.2246. Russian.
  4. Dreval AV. Osteoporoz, giperparatireoz i deficit vitamina D. Rukovodstvo. «GJeOTAR-Media», 2019; 160 s. Russian.
  5. Owens DJ, Fraser WD, Close GL. Vitamin D and the athlete: emerging insights. Eur J Sport Sci. 2015; 15 (1): 73–84. DOI: 10.1080/17461391.2014.944223.
  6. Federal'nye klinicheskie rekomendacii po diagnostike, lecheniju i profilaktike osteoporoza MZ RF. Problemy jendokrinologii. 2018; 63 (6): 392–426. DOI: 10.14341/probl2017636392-426. Russian.
  7. Mokrysheva NG, Eremkina AK, Mirnaja SS, i dr. Trudnosti differencial'noj diagnostiki mezhdu pervichnoj i vtorichnoj formami giperparatireoza. Ozhirenie i metabolizm. 2017; 14 (3): 48–53. Dostupno po ssylke: https://doi.org/10.14341/omet2017348-53. Russian.
  8. Qing H, Ardeshirpour L, Pajevic PD, et al. Demonstration of osteocytic perilacunar/canalicular remodeling in mice during lactation. J Bone Miner Res. 2012; 27 (5): 1018–29.
  9. Global Consensus Recommendations on Prevention and Management of Nutritional Rickets. J Clin Endocrinol Metab. 2016; 101 (2): 394–415.
  10. Song K, Kwon A, Chae HW, et al. Vitamin D status is associated with bone mineral density in adolescents: Findings from the Korea National Health and Nutrition Examination Survey. Nutr Res. 2021; 87: 13–21. DOI: 10.1016/j.nutres.2020.12.011.
  11. Yang G, Lee WYW, Hung ALH, et al. Association of serum 25(OH) Vit-D levels with risk of pediatric fractures: a systematic review and meta-analysis. Osteoporos Int. 2021 ; 32 (7): 1287–300. DOI: 10.1007/s00198-020-05814-1.
  12. Manson JE, Brannon PM, Rosen CJ, Taylor CL. Vitamin D Deficiency — Is There Really a Pandemic? N Engl J Med. 2016; 375: 1817–20. Available from: https://doi.org/10.1056/nejmp1608005.
  13. Sai AJ, Walters RW, Fang X, Gallagher JC. Relationship between Vitamin D, Parathyroid Hormone, and Bone Health. J Clin Endocrinol Metab. 2011; 96 (3): E436–E446. Available from: https://doi.org/10.1210/jc.2010-1886.
  14. Ginde AA, Wolfe P, Camargo CA, Schwartz RS. Defining vitamin D status by secondary hyperparathyroidism in the U.S. population. J Endocrinol Invest. 2012; 35: 42–48. Available from: https://doi.org/10.3275/7742.
  15. Monk RD, Bushinsky DA. Making Sense of the Latest Advice on Vitamin D Therapy. J Am Soc Nephrol. 2011; 22 (6): 994–8. Available from: https://doi.org/10.1681/ASN.2011030251.
  16. Olmos JM, Hernández JL, García-Velasco P, et al. Serum 25-hydroxyvitamin D, parathyroid hormone, calcium intake, and bone mineral density in Spanish adults. Osteoporos Int. 2016; 27 (1): 105–13. Available from: https://doi.org/10.1007/s00198-015-3219-6.
  17. Shen M, Li Z, Lv D, et al. Seasonal variation and correlation analysis of vitamin D and parathyroid hormone in Hangzhou, Southeast China. J Cell Mol Med. 2020; 24 (13): 7370–7. Available from: https://doi.org/10.1111/jcmm.15330.
  18. Al Quaiz AM, Mujammami M, Kazi A, et al. Vitamin D cutoff point in relation to parathyroid hormone: a population based study in Riyadh city, Saudi Arabia. Arch Osteoporos. 2019; 14 (1): 22. Available from: https://doi.org/10.1007/s11657-019-0565-6.
  19. Caroli B, Pasin F, Aloe R, et al. Characterization of skeletal parameters in a cohort of North Italian rugby players. J Endocrinol Invest. 2014; 37 (7): 609–17.
  20. Brzeziański M, Migdalska-Sęk M, Stuss M, et al. Effect of physical training on parathyroid hormone and bone turnover marker profile in relation to vitamin D supplementation in soccer players. Biology of Sport. 2022; 39 (4): 921–32. DOI: 10.5114/biolsport.2022.109956.
  21. Solarz K, Kopeć A, Pietraszewska J, et al. An evaluation of the levels of 25-hydroxyvitamin D3 and bone turnover markers in professional football players and in physically inactive men. Physiol Res. 2014; 63 (2): 237–43.
  22. Kljuchnikov SO, Kravchuk DA, Ogannisjan MG. Osteoporoz u detej i ego aktual'nost' dlja detskoj sportivnoj mediciny. Ros vestn perinatol i pediatr. 2017; 62 (3): 112–20. DOI: 10.21508/1027–4065–2017–62–3–112–120. Russian.
  23. Wyatt PB, Reiter CR, Satalich JR, et al. Effects of Vitamin D Supplementation in Elite Athletes: A Systematic Review. Orthopaedic Journal of Sports Medicine. 2024; 12 (1). DOI: 10.1177/23259671231220371.
  24. Thode J, et al. Comparison of serum total calcium, albumin-corrected total calcium, and ionized calcium in 1213 patients with suspected calcium disorders. Scand J Clin. Lab Invest England. 1989; 49 (3): 217–23.