ISSN Print 2713-2757
ISSN Online 2713-2765
SCIENTIFIC AND PRACTICAL REVIEWED JOURNAL OF FMBA OF RUSSIA
Copyright: © 2022 by the authors. Licensee: Pirogov University.
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (CC BY).
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (CC BY).
ORIGINAL RESEARCH
Evaluation of methods of avian leukemia virus inactivation in production of influenza vaccines
About authors
1 St. Petersburg Research Institute of Vaccines and Serums and Bacterial Preparations Production Company of the FMBA of Russia, St. Petersburg, Russia
2 Smorodintsev Research Institute of Influenza, St. Petersburg, Russia
Corresponding author: Alexey Alexandrovich Ekimov
Svobody, 52, Krasnoe Selo, St. Petersburg, 198320, Russia; ur.sviin@vomikeaa
About paper
Author contribution: all authors contributed equally to the research methodology design, data collection, analysis and interpretation, article authoring and editing.
Compliance with the ethical standards: the study was conducted in accordance with the ethical principles of the Declaration of Helsinki of 1964 and its subsequent revisions.
Received: 2022-10-31
Accepted: 2022-11-19
Published online: 2022-12-29
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Fig. 1. Dynamics of inactivation of the RAV-1 and RAV-2 avian leucosis virus strains with β-propiolactone
Fig. 2. Dynamics of inactivation of the RAV-1 and RAV-2 avian leucosis virus strains with UV radiation
Table. Reduction of the viral load by avian leucosis virus under the action of various inactivating agents
