ISSN Print 2713-2757
ISSN Online 2713-2765
SCIENTIFIC AND PRACTICAL REVIEWED JOURNAL OF FMBA OF RUSSIA
ORIGINAL RESEARCH
Evaluation of methods of avian leukemia virus inactivation in production of influenza vaccines
About authors
1 St. Petersburg Research Institute of Vaccines and Serums and Bacterial Preparations Production Company of the FMBA of Russia, St. Petersburg, Russia
2 Smorodintsev Research Institute of Influenza, St. Petersburg, Russia
Corresponding author: Alexey Alexandrovich Ekimov
Svobody, 52, Krasnoe Selo, St. Petersburg, 198320, Russia; ur.sviin@vomikeaa
About paper
Author contribution: all authors contributed equally to the research methodology design, data collection, analysis and interpretation, article authoring and editing.
Compliance with the ethical standards: the study was conducted in accordance with the ethical principles of the Declaration of Helsinki of 1964 and its subsequent revisions.
Received: 2022-10-31
Accepted: 2022-11-19
Published online: 2022-12-29
|
Fig. 1. Dynamics of inactivation of the RAV-1 and RAV-2 avian leucosis virus strains with β-propiolactone
Fig. 2. Dynamics of inactivation of the RAV-1 and RAV-2 avian leucosis virus strains with UV radiation
Table. Reduction of the viral load by avian leucosis virus under the action of various inactivating agents
