Funding: the study was supported by the funds of the State Assignment "Development of the Scheme for Complex Therapy of Infectious Diseases Caused by Antibiotic Resistant Pathogens Involving the Use of Bacteriophages or Their Derivatives in Combination with Antibacterials” (code: Bacteriophage-2). Typing of Klebsiella pneumoniae strains was supported by the Russian Science Foundation (project No. 22-15-00149, https://rscf.ru/project/22-15-00149/).

Author contribution: Gorodnichev RB, Kornienko MA — study plan, data acquisition and processing, manuscript writing; Bespiatykh DA — data processing; Malakhova MV — data acquisition; Veselovsky VA, Goloshchapov OV, Chukhlovin AB, Bespyatykh JA — data acquisition and processing, Shitikov EA — study plan, data processing, manuscript writing.

Compliance with ethical standards: experimental work was carried out in compliance with the guidelines SP 1.3.2322-08 "Safety of Working With Microorganisms of III—IV Groups of Pathogenicity (Danger) and Causative Agents of Parasitic Diseases"; guidelines SP 1.3.2518-09 “Additions and Amendments № 1 to the guidelines SP 1.3.2322-08 "Safety of Working With Microorganisms of III—IV Groups of Pathogenicity (Danger) and Causative Agents of Parasitic Diseases"; guidelines "Sanitary and Epidemiologic Requirements for the Handling of Medical Waste" (SanPiN 2.1.7.2790-10 SanPiN 3.3686-21, SanPiN 2.1.3684-21); Federal Clinical Guidelines "Rational Use of Bacteriophages in Clinical and Epidemiological Practice".