Acknowledgments: the authors express their deepest gratitude to the departed Doctor of Chemistry, Professor N. M. Alykov and Doctor of Medical Sciences, Professor N. N. Trizno for their invaluable contribution to the development of scientific ideas and areas investigated by the authors of the article.

Author contribution: Golovatskaya LI — idea and design of the mathematical part of the study, analysis, study planning, data interpretation; Trizno EV — idea and design of the experimental part, coordination of the study, participation in the practical part of the experiment, manuscript authoring; Smirnova YuA — participation in the development of mathematical program, literature selection and analysis, discussion of the results; Trizno MN — practical arrangement of the experiment, data visualization, statistical analysis.