ISSN Print 2713-2757
ISSN Online 2713-2765
SCIENTIFIC AND PRACTICAL REVIEWED JOURNAL OF FMBA OF RUSSIA
ORIGINAL RESEARCH
Computational phantom for a 5-year old child red bone marrow dosimetry due to incorporated beta emitters
About authors
1 Urals Research Center for Radiation Medicine of the Federal Medical-Biological Agency, Chelyabinsk, Russia
2 Chelyabinsk State University, Chelyabinsk, Russia
Correspondence should be addressed: Pavel A. Sharagin
Vorovskogo, 68-а, Chelyabinsk, 454141, Russia; ur.mrcru@nigarahs
About paper
Funding: the study was performed within the framework of the Federal Targeted Program "Ensuring Nuclear and Radiation Safety for 2016–2020 and for the Period up to 2035" and supported by the Federal Medical Biological Agency of Russia.
Author contribution: Sharagin PA — data acquisition, analysis and interpretation, manuscript writing and editing; Tolstykh EI — developing the research method; Shishkina EA — developing the concept, manuscript editing.
Received: 2023-10-23
Accepted: 2023-12-05
Published online: 2023-12-31
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Fig. Segmentation of the skeletal hematopoietic site of a 5-year-old child exemplified by the scapula. А. Skeleton of a 5-year-old child (skeletal sites with active hematopoiesis are highlighted in blue). B. Scapula. C. Scheme of bone division into BPS and BPS dimensions. G. BPS of the scapula — voxel representation, cross section (voxels simulating bone tissue are highlighted in black, those simulating RBM are highlighted in white)
Table 1. Mass fraction of RBM (% of the total mass of RBM in the skeleton) in the main hematopoietic sites of the 5-year-old child’s skeleton
Table 2. Chemical composition of simulated media adopted for all BPS
Table 3. Spongiosa parameters taken for BPS of a 5-year-old-child [11, 34–55] (coefficient of variation (CV) is given in parentheses, %)
Note: * — spongiosa parameters were calculated based on the measurement results of similar bones or based on the data for other age groups; the calculation method was reported previously in [25].
Table 4. Linear dimensions and thickness of the cortical layer taken for the BPS representing a 5-year-old child
Note: 1 — phantom shape was designated as follows: c — cylinder, dc — deformed cylinder, p — rectangular parallelepiped, e — ellipsoid; 2 — BPS dimensions were designated as follows: h — height; a — major axis (c), major axis for a larger base (dc) or side а (p); b — minor axis (c), minor axis for a large base (dc) or side b (p); с — major axis for a small base (dc); d — minor axis for a small base (dc); 3 — cortical layer thickness was considered to be different for the inner (medial) and outer (gluteal) surfaces of this segment of the ilium; 4 — BPS imitated only a part of the simulated bone segment, when the bone segment dimensions significantly exceeded 30 mm, since in such cases it makes no sense to simulate the entire bone fragment in terms of dosimetry [14, 21].
Table 5. Comparison of BPS volumes of 1-year-old and 5-year-old children
