Author contributions: Nechaykina OV — study conceptualization and design, data collection, data processing, article authoring; Laptev DS — study conceptualization and design, data collection, data processing, article editing; Bobkov DV — data processing, article editing; Petunov SG — data processing and interpretation, general guidance; Radilov AD — data processing and interpretation.

Compliance with ethical standards: the study was approved by the Ethics Committee of the Research Institute of Hygiene, Occupational Pathology and Human Ecology (Minutes #3 of July 21, 2022), and executed in compliance with the bioethics rules approved by the European Convention for the Protection of Vertebrate Animals used for Experimental and other Scientific Purposes. The animals were kept in accordance with GOST 33215-2014 Laboratory Animals Keeping Guidelines (edition of 2016).