2020 / 04

Следующая статья
DOI: 10.47183/mes.2020.014

ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ

Ключевые характеристики аутологичного биомедицинского продукта для коррекции дефекта хрящевой ткани

А. В. Еремеев1, О. А. Зубкова1, Е. С. Ручко1,2, М. А. Лагарькова, В. С. Сидоров, А. О. Рагозин
Информация об авторах

1 Федеральный научно-клинический центр физико-химической медицины Федерального медико-биологического агентства, Москва, Россия

2 Российский государственный аграрный университет — МСХА имени К. А. Тимирязева, Москва, Россия

Для корреспонденции: Артём Валерьевич Еремеев
ул. Малая Пироговская, д. 1а, 119435, г. Москва; ur.xednay@veemere-tra

Информация о статье

Финансирование: работа выполнена в рамках Государственного задания ФГБУ ФНКЦ ФХМ ФМБА России на период 2019–2020 г.

Благодарности: авторы благодарят заместителя директора по качеству АО НПО «Микроген» А. Ю. Богданова за консультацию в области контроля качества при производстве биомедицинских клеточных продуктов.

Вклад авторов: А. В. Еремеев — общее руководство написания обзора; О. А. Зубкова — сбор информации; Е. С. Ручко — сбор информации, оформление списка литературы; М. А. Лагарькова — редактирование статьи; В. С. Сидоров — анализ рынка биомедицинских клеточных продуктов; А. О. Рагозин — анализ информации по клиническим испытаниям.

Статья получена: 02.09.2020 Статья принята к печати: 02.10.2020 Опубликовано online: 20.11.2020
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  1. Madeira C, Santhagunam A, Salgueiro JB, Cabral JM. Advanced cell therapies for articular cartilage regeneration. Trends Biotechnol. 2015; 33 (1): 35–42.
  2. Atsuyuki I, Takashi I, A Hari Reddi. Human Stem Cells and Articular Cartilage Regeneration. Cells. 2012; 1 (4): 994–1009.
  3. Romo T, Kwak ES. Nasal grafts and implants in revision rhinoplasty. Facial Plast Surg Clin North Am. 2006; 14 (4): 373–87.
  4. Fulco I, Largo RD, Miot S, Wixmerten A, Martin I, Schaefer DJ, et al. Toward clinical application of tissue-engineered cartilage. Facial Plast Surg. 2013; 29 (2): 99–105.
  5. Martin I, Suetterlin R, Baschong W, Heberer M, Vunjak-Novakovic G, Freed LE. Enhanced cartilage tissue engineering by sequential exposure of chondrocytes to FGF-2 during 2D expansion and BMP-2 during 3D cultivation. J Cell Biochem. 2001; 83 (1): 121–8.
  6. Farhadi J, Fulco I, Miot S, Wirz D, Haug M, Dickinson SC, et al. Precultivation of engineered human nasal cartilage enhances the mechanical properties relevant for use in facial reconstructive surgery. Ann Surg. 2006; 244 (6): 978–85.
  7. Immerman S, White WM, Constantinides M. Cartilage grafting in nasal reconstruction. Facial Plast Surg Clin North Am. 2011; 19 (1): 175–82.
  8. Echeverry A, Carvajal J, Medina E. Alternative technique for tip support in secondary rhinoplasty. Aesthet Surg J. 2006; 26 (6): 662–8.
  9. Yilmaz S, Erçöçen AR, Can Z, Yenidünya S, Edali N, Yormuk E. Viability of diced, crushed cartilage grafts and the effects of Surgicel (oxidized regenerated cellulose) on cartilage grafts. Plast Reconstr Surg. 2001; 108 (4): 1054–60.
  10. Fatemi MJ, Hasani ME, Rahimian S, Bateni H, Pedram M, Mousavi SJ. Survival of block and fascial-wrapped diced cartilage grafts: an experimental study in rabbits. Ann Plast Surg. 2012; 69 (3): 326–30.
  11. Yenigun A, Meric A, Verim A, Ozucer B, Yasar H, Ozkul MH. Septal perforation repair: mucosal regeneration technique. Eur Arch Otorhinolaryngol. 2012; 269 (12): 2505–10.
  12. Галушко Е. А., Эрдес Ш. Ф., Алексеева Л. И. Остеоартроз в амбулаторной практике. Современная ревматология. 2012; 6 (4): 66–70.
  13. Lohmander LS. Knee replacement for osteoarthritis: facts, hopes, and fears Medicographia. 2013; 35: 181–8.
  14. Vos T, et al. Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2015; 386 (9995): 743–800.
  15. Amaral RJ, Pedrosa Cda S, Kochem MC, Silva KR, Aniceto M, et al. Isolation of human nasoseptal chondrogenic cells: a promise for cartilage engineering. Stem Cell Res. 2012; 8 (2): 292–9.
  16. Oseni AO, Butler PE, Seifalian AM. Optimization of chondrocyte isolation and characterization for large-scale cartilage tissue engineering. J Surg Res. 2013; 181 (1): 41–8.
  17. Rotter N, Bonassar LJ, Tobias G, Lebl M, Roy AK, Vacanti CA. Age dependence of cellular properties of human septal cartilage: implications for tissue engineering. Arch Otolaryngol Head Neck Surg. 2001; 127 (10): 1248–52.
  18. Haisch A, Marzahn U, Mobasheri A, Schulze-Tanzil G, Shakibaei M. Development and phenotypic characterization of a high density in vitro model of auricular chondrocytes with applications in reconstructive plastic surgery. Histol Histopathol. 2006; 21 (5): 467–76.
  19. Timur U, Caron M, Akker G, Windt A, Visser J, Rhijn L, et al. Increased TGF-β and BMP levels and improved chondrocyte-specific marker expression in vitro under cartilage-specific physiological osmolarity. Int J Mol Sci. 2019; 20 (4): 795.
  20. Tallheden T, Lee J, Brantsing C, Månsson JE, Sj–gren-Jansson E, Lindahl. A Human serum for culture of articular chondrocytes. Cell Transplant. 2005; 14 (7): 469–79.
  21. Fujisawa T, Hattori T, Ono M, Uehara J, Kubota S, Kuboki T, et al. CCN family 2/connective tissue growth factor (CCN2/ CTGF) stimulates proliferation and differentiation of auricular chondrocytes. Osteoarthritis Cartilage. 2008; 16 (7): 787–95.
  22. Malda J, Blitterswijk CA, Geffen M, Martens DE, Tramper J, Riesle J. Low oxygen tension stimulates the redifferentiation of dedifferentiated adult human nasal chondrocytes. Osteoarthritis Cartilage. 2004; 12 (4): 306–13.
  23. Haisch A, Marzahn U, Mobasheri A, Schulze-Tanzil G, Shakibaei M. Development and phenotypic characterization of a high density in vitro model of auricular chondrocytes with applications in reconstructive plastic surgery. Histol Histopathol. 2006 May; 21 (5): 467–76.
  24. Masuda K, Sah RL, Hejna MJ, Thonar EJ. A novel two-step method for the formation of tissue-engineered cartilage by mature bovine chondrocytes: the alginate-recovered-chondrocyte (ARC) method. J Orthop Res. 2003; 21 (1): 139–48.
  25. Ohyabu Y, Adegawa T, Yoshioka T, Ikoma T, Shinozaki K, Uemura T, et al. A collagen sponge incorporating a hydroxyapatite/ chondroitinsulfate composite as a scaffold for cartilage tissue engineering. J Biomater Sci Polym. 2009; 20 (13): 1861–74.
  26. Yanaga H, et al. Clinical application of cultured autologous human auricular chondrocytes with autologous serum for craniofacial or nasal augmentation and repair. Plast Reconstr Surg. 2006; 117: 2019–30.
  27. Yanaga H, Imai K, Fujimoto T, Yanaga K. Generating ears from cultured autologous auricular chondrocytes by using two-stage implantation in treatment of microtia. Plast Reconstr Surg. 2009; 124: 817–25.
  28. Yanaga H, Imai K, Yanaga K. Generative surgery of cultured autologous auricular chondrocytes for nasal augmentation. Aesthetic Plast Surg. 2009; 33: 795–802.
  29. Homicz MR, Schumacher BL, Sah RL, Watson D. Effects of serial expansion of septal chondrocytes on tissue-engineered neocartilage composition. Otolaryngol Head Neck Surg. 2002; 127 (5): 398–408.
  30. Yu H, Grynpas M, Kandel RA. Composition of cartilagenous tissue with mineralized and non-mineralized zones formed in vitro. Biomaterials. 1997; 18 (21): 1425–31.
  31. Alexander TH, Sage AB, Chen AC, Schumacher BL, Shelton E, Masuda K, et al. Insulin-like growth factor-I and growth differentiation factor-5promote the formation of tissue-engineered human nasal septal cartilage. Tissue Eng Part C Methods. 2010; 16 (5): 1213–21.
  32. Osch GJ, Veen SW, Marijnissen WJ, Verhaar JA. Monoclonal antibody 11-fibrau: a useful marker to characterize chondrocyte differentiation stage. Biochem Biophys Res Commun. 2001; 280 (3): 806–12.
  33. Kobayashi S, Takebe T, Zheng YW, Mizuno M, Yabuki Y, Maegawa J, et al. Presence of cartilage stem/progenitor cells in adult mice auricular perichondrium. PLoS One. 2011; 6 (10): e26393.
  34. Outani H, Okada M, Yamashita A, Nakagawa K, Yoshikawa H, Tsumaki N. Direct induction of chondrogenic cells from human dermal fibroblast culture by defined factors. PLoS One. 2013; 8 (10): e77365.
  35. Crowe N, Swingler TE, Le LT, Barter MJ, Wheeler G, Pais H, et al. Detecting new microRNAs in human osteoarthritic chondrocytes identifies miR-3085 as a human, chondrocyte-selective, microRNA. Osteoarthritis Cartilage. 2016; 24 (3): 534–43.
  36. Liu S, Takahashi M, Kiyoi T, Toyama K, Mogi M Genetic manipulation of calcium release-activated calcium channel 1 modulates the multipotency of human cartilage-derived mesenchymal stem cells. J Immunol Res. 2019; 2019: 7510214.
  37. Popko M, Bleys RL, De Groot JW, Huizing EH. Histological structure of the nasal cartilages and their perichondrial envelope. I. The septal and lobular cartilage. Rhinology. 2007; 45 (2): 148–52.
  38. Richmon JD, Sage A, Wong WV, Chen AC, Sah RL, Watson D. Compressive biomechanical properties of human nasal septal cartilage. Am J Rhinol. 2006; 20 (5): 496–501.
  39. Glasgold MJ, Kato YP, Christiansen D, Hauge JA, Glasgold AI, Silver FH. Mechanical properties of septal cartilage homografts. Otolaryngol Head Neck Surg. 1988; 99 (4): 374–9.
  40. Chang AA, Reuther MS, Briggs KK, Schumacher BL, Williams GM, Corr M, et al. In vivo implantation of tissue-engineered human nasal septal neocartilage constructs: a pilot study. Otolaryngol Head Neck Surg. 2012; 146 (1): 46–52.
  41. Reuther MS, Briggs KK, Neuman MK, Masuda K, Sah RL, Watson D. Shape fidelity of native and engineered human nasal septal cartilage. Otolaryngol Head Neck Surg. 2013; 148 (5): 753–7.
  42. Caffrey JP, Kushnaryov AM, Reuther MS, Wong VW, Briggs KK, Masuda K, et al. Flexural properties of native and tissue-engineered human septal cartilage. Otolaryngol Head Neck Surg. 2013; 148 (4): 576–81.
  43. Zou J, Bai B, Yao Y. Progress of co-culture systems in cartilage regeneration. Expert Opin Biol Ther. 2018; 18 (11): 1151–8.