In their line of duty, firefighters and rescuers are exposed to a combination of adverse factors, which necessitates monitoring their health. This review covers the most common variants of urticaria associated with high-risk occupations, such as cholinergic urticaria, food-induced anaphylaxis and exercise-induced urticaria, cold and stress-induced urticaria. The analysis includes the relevant research results published up to 2020; the discussion outlines the possible pathogenesis mechanisms of chronic urticaria.