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METHOD
Experimental justification of the maximum possible concentration (MPC) of dichlorohexafluorobutene in a working area
Research Institute of Hygiene, Occupational Pathology and Human Ecology of the Federal Medical Biological Agency, St. Petersburg, Russia
Correspondence should be addressed: Svelana A. Solnceva
Kapitolovo, str. 93, r.p. Kuzmolovsky, Vsevolozhsky r., Leningradskaja obl., 188663; ur.xobni@47.avecnlos
Author contribution: Shkaeva IE — study planning, literature analysis, data interpretation, rationale for setting the exposure standard, manuscript writing; Dulov SA — study planning, overall management; Nikulina OS, Solnceva SA — literature analysis, toxicological testing, data acquisition and analysis, manuscript writing; Zemlyanoi AV — research management, manuscript writing.
Compliance with ethical standards: laboratory animals were kept and fed in accordance with “Guidelines for Keeping Laboratory Animals in Vivariums of Research Institutes and Educational Institutions” (RD-APC 3.10.07.02-09 dated 15.12.2009), as well as with “Sanitary and Epidemiological Requirements for the Device, Equipment and Maintenance of Experimental Biological Clinics (Vivariums)” (SP 2.2.1.3218-14 dated 29.08.2014).