Funding: the study was carried out within the framework of the State assignment of Russian Federal Medical Biological Agency “Human Cell-Mediated Immunity During Realization of Chronic Radiation Exposure Late Effects” (code 27.002.20.800).

Author contribution: Blinova EA — literature analysis, experimental procedure, data processing, manuscript writing; Nikiforov VS — literature analysis, experimental procedure, manuscript writing; Yanishevskaya MA — experimental procedure, manuscript editing; Akleyev AV — general management, manuscript writing.

Compliance with ethical standards: the study was approved by the Ethics Committee of Ural Research Center for Radiation Medicine of Russian Federal Medical Biological Agency (protocol № 2 dated July 20, 2021).The informed consent was submitted by all examined individuals.