2023 / 02

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DOI: 10.47183/mes.2023.020

ORIGINAL RESEARCH

The relationship between the variants of immune response and the cortisol and adrenaline levels associated with cooling

Patrakeeva VP, Kontievskaya EV
About authors

N. Laverov Federal Center for Integrated Arctic Research, Ural Branch of the Russian Academy of Sciences, Arkhangelsk, Russia

Correspondence should be addressed: Veronika P. Patrakeeva
Nikolsky prospect, 20, Arkhangelsk, 163020, Russia; ur.xednay@akinorev.aweekartap

About paper

Funding: the study was performed as part of the Program of Fundamental Scientific Research on the topic of the environmental immunology laboratory, Institute of Physiology of Natural Adaptations, N. Laverov Federal Center for Integrated Arctic Research, Ural Branch of the Russian Academy of Sciences (project № 122011300377-5).

Author contribution: Patrakeeva VP — study planning, data acquisition, processing and interpretation, literature review, manuscript writing; Kontievskaya EV — data acquisition and processing, literature review.

Compliance with ethical standards: the study was approved by the Ethics Committee of the N. Laverov Federal Center for Integrated Arctic Research, the Ural branch of RAS (protocol № 4 of 7 December 2016, protocol № 6 of 14 February 2022) and conducted in accordance with the principles of the Declaration of Helsinki (1975, rev. 2013).

Received: 2023-05-10 Accepted: 2023-06-10 Published online: 2023-06-26
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Fig. 1. Changes in cortisol levels after the whole body cooling; * — p < 0.01
Fig. 2. Changes in adrenaline levels after the whole body cooling; * — р < 0.01
Fig. 3. Ferritin concentrations before and after the whole body cooling. * — p3 < 0.01 (significance of differences of 0.01 in the volunteers of group 3 before and after the whole body cooling); ● — р1–3, 2–3 < 0.01 (significance of differences of 0.01 between the volunteers of groups 1 and 3 and groups 2 and 3, respectively, before the whole body cooling)