ISSN Print 2713-2757
ISSN Online 2713-2765
SCIENTIFIC AND PRACTICAL REVIEWED JOURNAL OF FMBA OF RUSSIA
Copyright: © 2023 by the authors. Licensee: Pirogov University.
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (CC BY).
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (CC BY).
ORIGINAL RESEARCH
Computational red bone marrow dosimetry phantom of a one-year-old child enabling assessment of exposure due to incorporated beta emitters
About authors
1 Ural Research Center for Radiation Medicine, Chelyabinsk, Russia
2 Chelyabinsk State University, Chelyabinsk, Russia
Correspondence should be addressed: Pavel A. Sharagin
Vorovsky st., 68 A, Chelyabinsk, 454141, Russia; ur.mrcru@nigarahs
About paper
Funding: the work was part of the Federal Target Program "Ensuring Nuclear and Radiation Safety for 2016-2020 and up to 2035", with financial support from the Federal Medical Biological Agency of Russia.
Author contribution: Sharagin PA — data generation, analysis, interpretation, manuscript authoring and editing; Tolstykh EI — study methodology development, manuscript editing; Shishkina EA — conceptualization, manuscript editing.
Received: 2023-06-14
Accepted: 2023-08-23
Published online: 2023-09-26
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Fig. Segmentation of a hematopoietic site of a one-year-old child's skeleton using the example of humerus. A. Skeleton of a one-year-old child (active hematopoietic sites are highlighted blue). B. Humerus. C. Pattern of division of the bone into BPSs and their dimensions. D. BPS of humerus in voxel representation, a sectional view (black voxels imitate bone, white — BM)
Table 1. AM mass fraction (% of the total AM mass fraction in the skeleton) in the main hematopoietic sites of a one-year-old child's skeleton [15].
Table 2. Chemical composition of the modeled media (all BPS)
Table 3. Spongiosa parameters assumed for BPSs of a one-year-old child [32–42] (CV is given in parentheses, %)
Note: * — spongiosa parameters calculated based on measurements of similar bones or data for other ages; the method of calculation has been described previously [20].
Table 4. Linear dimensions and cortical layer thickness assumed for BPSs of a one-year-old child
Note: 1 — the shape of a phantom was designated as follows: c — cylinder, dc — deformed cylinder, p — rectangular parallelepiped, e — ellipsoid; 2 — dimensions of the BPSs: h — height; a — major axis (c), major axis for a larger base (dc) or side a (r); b — minor axis (c), minor axis for a larger base (dc) or side b (r); c — major axis for smaller base (dc); d — minor axis for smaller base (dc); for ellipsoid (e), a, b, c are the axes; 3 — different cortical layer thickness values were taken for inner (medial) and outer (gluteal) surfaces of this segment of the iliac bone (see Figure); 4 — BPS simulated only part of a modeled bone segment when dimensions thereof significantly exceeded 30 mm, since in such cases from the point of view of dosimetry it makes no sense to model the entire segment [13, 16].
Table 5. Comparison of the volumes of BPSs, newborn and one-year-old child
