Funding: this study was carried out in the framework of state assignment of the FMBA of Russia, subject "State of human cellular immunity during realization of long-term effects of chronic radiation exposure."

Acknowledgments: authors thank Startsev NV, Head of the "Human Being" Database Department of the Urals Research Center for Radiation Medicine of the FMBA of Russia, for the data provided; Litvinenko NP, senior laboratory assistant at the Laboratory of Molecular Cellular Radiobiology of the Urals Research Center for Radiation Medicine of the FMBA of Russia, for assistance in conducting the experiment.

Author contribution: Kodintseva EA — study concept and design, experimental work, analysis and statistical processing of the data, article authoring; Akleev AA — study concept, interpretation of the results, article editing.

Compliance with ethical standards: the study was approved by the Ethics Committee of the Urals Research Center for Radiation Medicine of the FMBA of Russia (Minutes #3 of June 8, 2023). Participants of the study signed a voluntary informed consent in conformity with the 2013 Declaration of Helsinki.