Author contribution: Vakunenkova OA — experimental part of the study; Zolotoverkhaya EA — blood biochemistry testing; Pechurina TB — tissue biochemistry testing; Schäfer TV — experimental part of the study, data processing and visualization, developing the experimental model; Ivnitsky JuJu — research design, developing the experimental model, data interpretation and discussion. All authors contributed to discussion, manuscript writing and editing.

Compliance with ethical standards: the study was compliant with the principles of bioethics adopted by the European Convention for the Protection of Vertebrate Animals used for Experimental and Other Scientific Purposes.